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ホーム製品情報化学原料染料中間体生薬脂質調節薬ロバスタチンCAS75330-75-5
  • 生薬脂質調節薬ロバスタチンCAS75330-75-5
  • 生薬脂質調節薬ロバスタチンCAS75330-75-5
  • 生薬脂質調節薬ロバスタチンCAS75330-75-5
  • 生薬脂質調節薬ロバスタチンCAS75330-75-5
  • 生薬脂質調節薬ロバスタチンCAS75330-75-5
  • 生薬脂質調節薬ロバスタチンCAS75330-75-5

生薬脂質調節薬ロバスタチンCAS75330-75-5

Payment Type:
L/C,T/T,D/P,Paypal,Money Gram,Western Union
Incoterm:
FOB,FCA,CIP
Min. Order:
1 Kilogram
Delivery Time:
1 Days
Transportation:
Ocean,Land,Air
Port:
Shanghai,Qingdao
Share:
  • 製品の説明
Overview
Product Attributes

モデル75330-75-5

ブランドミンヤ

Supply Ability & Additional Informations

包装25kg /ドラム

生産高5000mt One Year

輸送方法Ocean,Land,Air

原産地中国

供給能力1000kg

認証 state-owned enterprise

HSコード2932999099

ポートShanghai,Qingdao

お支払い方法の種類L/C,T/T,D/P,Paypal,Money Gram,Western Union

IncotermFOB,FCA,CIP

納期1 天数

Packaging & Delivery
Selling Units:
Kilogram
Package Type:
25kg /ドラム

化学原料ロバスタチンCAS75330-75-5

Purpose:

Lovastatin is a kind of HMG CoA reductase inhibitor which is used to reduce the cell permeability of cholesterol.
effect:
1. Lipid regulating effect
Lovastatin can block the synthesis of endogenous cholesterol by inhibiting HMG CoA reductase, which is the rate limiting enzyme of cholesterol synthesis. Lovastatin can reduce the content of cholesterol in cells, increase the number of LDL receptors on cell surface, accelerate the uptake and degradation of LDL particles in blood circulation, and reduce the total cholesterol, very low density lipoprotein (VLDL), LDL and triglyceride in plasma. Since the conversion of HMG CoA to mevalonate is an early step in cholesterol biosynthesis pathway, lovastatin does not lead to accumulation of potentially toxic cholesterol substances. HMG CoA can also be quickly reversed into acetyl coenzyme A and participate in other biosynthetic pathways in vivo. This inhibition is incomplete and reversible, and there is a dose-response relationship, Therefore, lovastatin has a significant effect on reducing blood lipid and has less side effects.
Generally speaking, lovastatin mainly plays a role in the following aspects: ① competitive inhibition of HMG CoA reductase activity and reduction of endogenous cholesterol synthesis; ② increase of LDL receptor expression in hepatocytes and increase receptor mediated plasma LDL clearance rate; ③ inhibit migration and proliferation of smooth muscle cells; ④ reduce assembly and secretion of liver lipoprotein.
2. Non lipid regulating effect
Lovastatin can not only significantly reduce blood lipid, but also significantly improve the function of endothelial cells, promote the production of nitric oxide synthase (eNOS), thus increasing the synthesis and release of no, which plays a key role in maintaining normal pulmonary vascular tension and reversing hypoxia induced pulmonary vasoconstriction and vascular remodeling. In addition, lovastatin has anti-inflammatory and antiproliferative effects, which can inhibit the proliferation of mesangial cells and the secretion of extracellular matrix, so as to reduce glomerulosclerosis.

English alias:

Antibiotic MB 530B
Altoprev
Rovacor
6a-Methylcompactin

Name:                     Lovastatin  

Cas No:

CAS 75330-75-5
MF: C24H36O5
Appearance:
White Powder
purity:
>99%
Brand Name:
Ming ya
Delivery time:
Within 1-3 days payment
Export Markets:
Global


 Lovastatin CAS 75330-75-5


 Lovastatin CAS 75330-75-5

 Lovastatin CAS 75330-75-5

その他の製品カテゴリ:

1、化学原料

2、ファインケミカル

3、生薬

4、医薬品中間体

5、その他の化学製品

私たちの会社は輸出入貿易に従事する専門家であり、10種類以上の製品、数百の製品があり、製品の種類は非常に豊富です、私たちは常に最高品質の製品、より多くの製品の詳細を提供するために最も優先的な価格を主張してきました、お問い合わせを歓迎します。

製品グループ : 化学原料 > 染料中間体

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